hCLDN6(Claudin6)/MC-38
CBPG0050
詢 價
留 言
產品描述
產品數據庫
| I. Background | |||
|
CLDNs 是上皮細胞緊密連接的主要成分。CLDN6 是緊密連接家族（CLDNs）的一員，是一個四次跨膜蛋白，具有較短的胞質 N 端和 C 端胞質結構域、兩個胞外結構域（較大的 ECL1 和較小的 ECL2）和一個短的胞內環(huán)。CLDN6 可參與乳腺癌、胃癌、肝細胞癌等多種惡性腫瘤的發(fā)生發(fā)展。CLDN6 具有重要的生物學功能，其異常表達與丙型肝炎感染有關。
|
|||
| II. Introduction | |||
| Host Cell: | MC-38 | ||
| Expressed gene: | hCLDN6(Claudin6) | ||
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | ||
| Freeze Medium: | 90% FBS+10% DMSO | ||
| Culture Medium: | DMEM+10%FBS+2ug/ml puromycin | ||
| Mycoplasma Testing: | Negative | ||
| Storage: | Liquid nitrogen | ||
| III. Description of Host Cell Line | |||
| Organism: | Mus musculus, mouse | ||
| Tissue: | Colon | ||
| Morphology: | Epitheloid cell | ||
| Growth Properties: | Adherent | ||
| IV. Representative Data | |||
|
Figure 1. Recombinant hCLDN6(Claudin6)/MC38 stably expressing CLDN6. |
|||
